Face transplant recipient’s donor face now failing

Face transplant recipient’s donor face now failing

More than 40 patients worldwide have received face transplants

A woman who was severely burned in a domestic violence attack in Vermont is hoping for a second face transplant after doctors recently discovered tissue damage that likely will lead to the loss of her donor face.

Carmen Blandin Tarleton, 51, was burned over 80% of her body when her estranged husband beat her with a baseball bat and doused her body with lye in 2007. Six years ago, she received a face transplant at Brigham and Woman’s Hospital in Boston, where she’s being evaluated for a possible second transplant.

Tarleton, who now lives in Manchester, New Hampshire, told The Boston Globe she has no regrets about the transplant because it dramatically improved her life. She has learned to play the piano and banjo, wrote a memoir and has spoken to many groups about her life. She lost 20 pounds and began walking five miles a week.

“I had such a low quality of life prior to my face transplant. Do I wish it had lasted 10 or 20 years? Of course,” she said.

More than 40 patients worldwide have received face transplants, including 15 in the United States. None of the American patients have lost their donor faces, but last year, a French man whose immune system rejected his donor face eight years after his first transplant underwent a second.

Tarleton’s doctors noted that most transplanted organs have limited life spans. But her situation is a reminder that despite successes in the field, face transplantation is experimental and still a young science with many unanswered questions about benefits versus long-term risks.

“There are so many unknowns and so many new things we are discovering,” said Dr. Bohdan Pomahac, director of plastic surgery transplantation at the Brigham and one of Tarleton’s surgeons. Still, he said, “it’s really not realistic to hope faces are going to last (the patient’s) lifetime.”

READ MORE: US begins organ transplants from living donors who have HIV

Dr. Brian Gastman, a transplant surgeon at the Cleveland Clinic, which did the first U.S. face transplant 11 years ago, said more patients are starting to experience chronic rejection. “We all believe every patient will likely need a retransplant” at some point, he said.

Since her transplant in February 2013, Tarleton has had repeated rejection episodes when her new face became swollen and red. Those episodes were successfully treated, but last month, physicians discovered that some blood vessels to her face had narrowed and closed, causing facial tissue to die. If the damage progresses slowly, she could go on the wait list for another donor face. Under the worst case scenario, the tissue would die quickly, and doctors would have to remove it and reconstruct her original face.

“We all know we are in unchartered waters,” she said. “I would rather not have to go through a catastrophic failure.”

It will take at least a month to evaluate Tarleton and reach a decision about a second transplant, doctors said. Aside from the setback with her face, a synthetic cornea transplanted into her left eye recently failed, leaving her almost blind.

“These are not common things to go wrong, but when things go wrong, you have to deal with it,” she said. “l will get back to where I was. How, I don’t know. I will get through this.”

The Associated Press

READ MORE: Organ donation week particularly personal for Comox Valley nurse

Like us on Facebook and follow us on Twitter

Just Posted

The Government of Alberta identified 115 new COVID-19 cases Sunday, bringing the provincial total to 3,089.
(Black Press file photo)
Red Deer COVID cases continue to fall

114 cases in Red Deer, down one from Saturday

File Photo
Blackfalds RCMP seeking suspects in traffic collision

RCMP are asking the public for help identifing two suspects wanted for multiple offences

Maskwacis Pride crosswalk (Left to right): Montana First Nation Councillor Reggie Rabbit, Samson Cree Nation Councillor Louise Omeasoo, Samson Cree Nation Councillor Katherine Swampy, Samson Cree Nation Councillor Shannon Buffalo, Samson Cree Nation Chief Vern Saddleback.
Pride in Maskwacis

The 4th inaugural Maskwacis Pride crosswalk painting took place on Saturday 12, 2020.

Alberta Premier Jason Kenney arrives at the 2021 budget in Edmonton on Thursday, Feb. 25, 2021.THE CANADIAN PRESS/Jason Franson
Alberta launches COVID vaccine lottery with million-dollar prizes to encourage uptake

The premier says the lottery will offer three prizes worth $1 million a piece, as well as other prizes

The City of Red Deer sits at 249 active cases of the virus, after hitting a peak of 565 active cases on Feb. 22. (Black Press file image)
Red Deer down to 119 active COVID-19 cases

Province identifies 179 new cases Saturday

Canadian Prime Minister Justin Trudeau participates in a plenary session at the G7 Summit in Carbis Bay, England on Friday June 11, 2021. THE CANADIAN PRESS/Adrian Wyld
Canada donating 13M surplus COVID-19 vaccine doses to poor countries

Trudeau says the government will pay for 87 million shots to be distributed to poor countries

Montreal Canadiens goaltender Carey Price (31) is scored on by Vegas Golden Knights defenseman Alec Martinez, not pictured, during the second period in Game 1 of an NHL hockey Stanley Cup semifinal playoff series Monday, June 14, 2021, in Las Vegas. (AP Photo/John Locher)
Habs fall 4-1 to Vegas Golden Knights in Game 1 of NHL semifinal series

Match was Montreal’s first game outside of Canada in 2021

The Kamloops Indian Residential School is photographed using a drone in Kamloops, B.C., Monday, June, 14, 2021. The remains of 215 children were discovered buried near the former school earlier this month. THE CANADIAN PRESS/Jonathan Hayward
Communities grapple with what to do with former residential and day schools

Some tear them down as a tool to help healing, others repurpose them as tools for moving forward

RCMP Const. Shelby Patton is shown in this undated handout photo. RCMP say that Patton was hit by an allegedly stolen truck that he had pulled over on Saturday morning in Wolseley, east of Regina. THE CANADIAN PRESS/HO, RCMP
Pair charged in Saskatchewan Mountie’s death make first court appearance

Const. Shelby Patton was hit by an allegedly stolen truck that he had pulled over Saturday morning

David and Collet Stephan leave for a break during an appeal hearing in Calgary on Thursday, March 9, 2017. THE CANADIAN PRESS/Todd Korol
Appeal Court rejects stay for Alberta couple facing third trial in son’s death

Pair accused in their earlier trials of not seeking medical attention for their son sooner

Calgary Stampeders’ Jerome Messam leaps over a tackle during second half CFL western semifinal football action in Calgary, Sunday, Nov. 15, 2015.THE CANADIAN PRESS/Jeff McIntosh
CFL football will be played this summer in Canada

Governors vote unanimously in favour to start the ‘21 campaign on Aug. 5

Citizenship Minister Marco Mendicino holds a press conference in Ottawa on Thursday, Nov. 12, 2020. The federal government is announcing that Indigenous people can now apply to reclaim their names on passports and other government documents. THE CANADIAN PRESS/Sean Kilpatrick
Indigenous people can now reclaim traditional names on their passports and other ID

Announcement applies to all individuals of First Nations, Inuit and Métis background

This undated photo provided by Girl Scouts of New Mexico Trails shows a scout donating cookies to firefighters in Rio Rancho, New Mexico, as part of the Hometown Heroes program. As the coronavirus pandemic wore into the spring selling season, many Girl Scout troops nixed their traditional cookie booths for safety reasons. That resulted in millions of boxes of unsold cookies. (Girl Scouts of New Mexico Trails via AP)
Thinner Mints: Girl Scouts have millions of unsold cookies

Since majority of cookies are sold in-person, pandemic made the shortfall expected

In this artist’s sketch, Nathaniel Veltman makes a video court appearance in London, Ont., on June 10, 2021 as Justice of the Peace Robert Seneshen (top left) and lawyer Alayna Jay look on. THE CANADIAN PRESS/Alexandra Newbould
Terror charges laid against London attack suspect

Crown says Nathaniel Veltman’s four counts of first-degree murder constitute an act of terrorism

Most Read